Shaken Single Use Bioreactors with PID Control for Mammalian Cell Culture

1. Equipped with an intuitive touchscreen interface, the system utilizes a high-precision TMFC mass flow meter for blending air, CO, and O. Integrated with next-generation high-precision fiber-optic pH and fiber-optic DO (dissolved oxygen) technology, alongside PLC control protocols, it enables comprehensive monitoring and automated regulation of critical parameters including CO and O levels.

2. The bioreactor’s fully automatic feedback controller leverages advanced PID feedback control technology to conduct full-process monitoring of cell cultures, ensuring a more stable and reliable cultivation process.

3. The control system supports data acquisition, real-time curve logging, historical record retrieval, result comparison, and report generation—all compliant with regulatory requirements.

4. Operates within a sealed environment for single-use processes, minimizing contamination risks. Cultivated products can be directly frozen, thawed, and harvested without additional handling.

5. Excellently caters to adherent cell culture needs while addressing the challenges of adherent cell scale-up, thanks to its large specific surface area.

6. For adherent cell cultures, continuous perfusion cultivation can be effortlessly implemented.

7. Provides a dynamic cultivation environment that offers superior growth conditions compared to traditional cell reactors.

8. Serves as a viable alternative to cell factories and spinner flasks for cell seed and virus seed preparation workflows.

9. Compatible with suspension culture requirements of other traditional rockers available on the market.

10. Facilitates feasible enzymatic digestion, transfer, and scale-up of cell cultures.

11. Can be paired with an appropriate microscope for direct, real-time observation of cell cultures.