Triple & Quintuple Conjoined Glass Bioreactor with Siemens PLC Control for Medium Formulation Screening

Triple and quintuple conjoined glass bioreactors are laboratory-scale glass fermentation systems designed for intuitive operation and high performance, supporting diverse fermentation modes including batch, fed-batch, and animal cell culture applications. An integrated color touchscreen presents all real-time measured values and control parameters, streamlining user operation significantly. Each reactor vessel is outfitted with 4 peristaltic pumps positioned at the front, enabling precise delivery of acid, alkali, antifoam agent, and culture medium to the fermentation tank. Key fermentation parameters including pH, dissolved oxygen (DO), temperature, and agitation speed are real-time monitored via the controller, with all data and control settings transmissible to the controller or a connected computer. With a compact footprint, all system components are seamlessly integrated into the fermentation setup. Agitation is achieved via either top-driven direct-coupling mechanical stirring or bottom-driven magnetic indirect-coupling mechanical stirring, offering a simplified structure with stable, consistent operation.

Application areas:

• Identify secondary metabolites or novel enzyme activities in heterogeneous mixed culture systems;

• High-throughput screening studies, mutant strain distribution analyses, and construction of E. coli or yeast libraries;

• Metabolic flux investigations and high-throughput screening of high-activity mutant strains;

• Comparative research, including isolation and screening of clinical strains;

• Optimization of growth media for cell lines or high-yield microbial strains;